60 Minutes
Treatment
Polyneucleotides

Treatment at a glance
Treatment time
Discomfort
Mild to moderate
Back to work
Yes - personal preference
Treatment interval
Every 3-4 weeks
Downtime
Slight swelling, redness in area post injection
Minimum treatments required
3 sessions
Treatment time
60 Minutes
Discomfort
Mild to moderate
Back to work
Yes - personal preference
Treatment interval
Every 3-4 weeks
Downtime
Slight swelling, redness in area post injection
Minimum treatments required
3 sessions
Polynucleotides represent the next generation of regenerative biotherapy—an advanced approach to deep skin renewal that works at a cellular level.
These biocompatible molecules, derived from highly purified DNA fragments, stimulate fibroblast activity, boost collagen synthesis, and enhance tissue hydration, helping to repair and rejuvenate the skin from within.
TREATMENT OPTIONS
When injected intradermally, polynucleotides promote skin repair, improve resilience, and support long-term radiance—making them ideal for clients seeking deep dermal regeneration, a firmer complexion, and visibly healthier skin.
PDRN RESTORE – PLINEST
A regenerative biotherapy using highly purified polynucleotides to stimulate fibroblast activity, improve tissue repair, and restore skin health. PDRN Restore is ideal for clients seeking skin regeneration, improved texture, and enhanced resilience.
PDRN + HA REVIVE
Our latest formulation combines polynucleotides with hyaluronic acid, offering a hybrid solution that delivers the deep regenerative benefits of PDRN alongside intense hydration. This advanced treatment helps to firm, plump, and smooth the skin for a fresher, more rejuvenated appearance.
Key Benefits
what this treatment offers
- Stimulates natural skin cell regeneration for youthful, resilient skin
- Reduces fine lines and wrinkles by stimulating collagen and elastin production
- Improves skin texture, tone, and elasticity
- Calms inflammation and reduces redness or irritation—ideal for sensitive skin
- Smooths and refines acne scars and uneven skin texture
- Deeply hydrates and nourishes the skin for long-term rejuvenation
- Supports overall skin vitality for a fresher, more radiant complexion
FAQs
What is the difference between PDRN Restore and PDRN + HA Revive?
PDRN Restore (Plinest) focuses on cellular repair and regeneration by stimulating fibroblast activity. PDRN + HA Revive is a hybrid formulation that combines the regenerative benefits of PDRN with the hydrating and plumping effects of hyaluronic acid—offering a comprehensive solution for skin repair, hydration, and rejuvenation.
Who is suitable for polynucleotide treatments?
Polynucleotide treatments are ideal for clients seeking a gentle, yet powerful solution for ageing, sagging skin, fine lines, and wrinkles. They are particularly suitable for sensitive skin types, as well as those struggling with acne scars, enlarged pores, uneven skin tone, and dull, dehydrated skin.
How many treatments will I need?
A course of 3–4 treatments spaced 3–4 weeks apart is typically recommended for optimal results, followed by maintenance treatments as needed. Your practitioner will advise you on a personalised plan during your consultation.
Is there downtime?
Mild redness or small bumps at the injection sites may occur, but these typically subside within a few days. Most clients return to normal activities shortly after treatment.
When will I see results?
Many clients notice a subtle glow and improved hydration after the first treatment, with continued improvements in skin texture, tone, and firmness developing over time as the skin regenerates.