60 Minutes
Treatment
Polyneucleotides

Treatment at a glance
Treatment time
Discomfort
Mild to moderate
Back to work
Yes - personal preference
Treatment interval
Every 3-4 weeks
Downtime
Slight swelling, redness in area post injection
Minimum treatments required
3 sessions
Treatment time
60 Minutes
Discomfort
Mild to moderate
Back to work
Yes - personal preference
Treatment interval
Every 3-4 weeks
Downtime
Slight swelling, redness in area post injection
Minimum treatments required
3 sessions
Advanced Regenerative Skin Therapy
Polynucleotides are a regenerative injectable treatment designed to improve skin quality, hydration, and resilience from within. At MAESKN, they are used to help strengthen fragile skin, soften fine lines, improve texture, calm redness, support acne scarring, and encourage collagen banking for healthier, more resilient skin over time.
Rather than adding volume, polynucleotides support the skin’s natural repair process—making them ideal for clients wanting subtle, natural-looking rejuvenation.
WHAT ARE POLYNUCLEOTIDES?
In Simple Terms
Polynucleotides are highly purified DNA fragments that help the skin repair, hydrate, and regenerate itself. They work by supporting collagen production, improving skin strength, and calming inflammation.
Key Benefits
what this treatment offers
- Stimulates natural skin cell regeneration for youthful, resilient skin
- Reduces fine lines and wrinkles by stimulating collagen and elastin production
- Improves skin texture, tone, and elasticity
- Calms inflammation and reduces redness or irritation—ideal for sensitive skin
- Smooths and refines acne scars and uneven skin texture
- Deeply hydrates and nourishes the skin for long-term rejuvenation
- Supports overall skin vitality for a fresher, more radiant complexion
WHO IS THIS TREATMENT FOR?
This treatment is ideal for clients concerned with:
- fine lines and early ageing
- tired, dull, or dehydrated skin
- sensitive or fragile skin
- under-eye ageing and dark circles
- acne scarring
- redness and inflammation
- enlarged pores
- uneven tone and texture
TREATMENT OPTIONS
PDRN Restore – Plinest
A regenerative treatment focused on skin repair, firmness, and resilience.
Recommended as a course of 3 treatments.
PDRN + HA Revive
A hybrid treatment combining polynucleotides with hyaluronic acid for regeneration plus added hydration and smoothness.
Recommended as a course of 3 treatments.
FAQs
What is the difference between PDRN Restore and PDRN + HA Revive?
PDRN Restore (Plinest) focuses on cellular repair and regeneration by stimulating fibroblast activity. PDRN + HA Revive is a hybrid formulation that combines the regenerative benefits of PDRN with the hydrating and plumping effects of hyaluronic acid—offering a comprehensive solution for skin repair, hydration, and rejuvenation.
Who is suitable for polynucleotide treatments?
Polynucleotide treatments are ideal for clients seeking a gentle, yet powerful solution for ageing, sagging skin, fine lines, and wrinkles. They are particularly suitable for sensitive skin types, as well as those struggling with acne scars, enlarged pores, uneven skin tone, and dull, dehydrated skin.
How many treatments will I need?
A course of 3–4 treatments spaced 3–4 weeks apart is typically recommended for optimal results, followed by maintenance treatments as needed. Your practitioner will advise you on a personalised plan during your consultation.
Is there downtime?
Mild redness or small bumps at the injection sites may occur, but these typically subside within a few days. Most clients return to normal activities shortly after treatment.
When will I see results?
Many clients notice a subtle glow and improved hydration after the first treatment, with continued improvements in skin texture, tone, and firmness developing over time as the skin regenerates.