60 Minutes
Treatment
Polyneucleotides

Treatment at a glance
Treatment time
Discomfort
Mild to moderate
Back to work
Yes - personal preference
Treatment interval
Every 3-4 weeks
Downtime
Slight swelling, redness in area post injection
Minimum treatments required
3 sessions
Treatment time
60 Minutes
Discomfort
Mild to moderate
Back to work
Yes - personal preference
Treatment interval
Every 3-4 weeks
Downtime
Slight swelling, redness in area post injection
Minimum treatments required
3 sessions
Restore. Regenerate. Rejuvenate.
Discover a regenerative approach to skin rejuvenation with polynucleotides
Designed to improve skin quality from within, polynucleotides support the skin’s natural repair and renewal processes, helping to improve hydration, elasticity, texture and overall skin resilience.
Whether you’re looking to rejuvenate tired-looking eyes, soften fine lines, improve redness-prone skin or restore a healthier, more radiant complexion, polynucleotides offer a subtle, natural-looking approach to skin rejuvenation.
WHAT ARE POLYNUCLEOTIDES?
In Simple Terms
Polynucleotides are highly purified DNA fragments that help the skin repair, hydrate, and regenerate itself. They work by supporting collagen production, improving skin strength, and calming inflammation.
Key Benefits
what this treatment offers
- Under-Eye Rejuvenation – Helps improve dark circles, fine lines and crepey skin.
- Redness & Skin Resilience – Supports skin repair and helps calm redness-prone skin.
- Improved Skin Quality & Texture – Promotes smoother, healthier and more resilient skin.
- Fine Lines – Supports collagen production and improves skin elasticity.
- Hydration & Radiance – Boosts hydration for a plumper, brighter and more radiant complexion.
Who is this for
This treatment is ideal for clients concerned with:
- fine lines and early ageing
- tired, dull, or dehydrated skin
- sensitive or fragile skin
- under-eye ageing and dark circles
- redness and inflammation
- uneven tone and texture
What to Expect During Your Treatment
1. Consultation & Skin Assessment
Every treatment begins with a consultation to assess your skin concerns, medical history and suitability for polynucleotides.
We discuss your goals and recommend a personalised treatment plan, whether focusing on the under-eye area or overall skin quality.
2. Your Polynucleotide Treatment
The skin is cleansed and prepared before the polynucleotide solution is carefully administered through a series of small injections into the targeted area.
The procedure typically takes 30–45 minutes, depending on the area being treated.
3. Recovery & Aftercare
Small raised bumps, redness or mild swelling may appear immediately after treatment. These generally settle within a few days, although bruising can occasionally last longer.
Aftercare advice will be provided to support your recovery.
4. Gradual Skin Regeneration
Unlike treatments designed to create immediate volume, polynucleotides work gradually.
Improvements in hydration, texture and overall skin quality may become noticeable over several weeks, with results developing throughout the recommended treatment course.
Our Treatments
Polynucleotides – Under-Eye Rejuvenation
Brighter, smoother, fresher-looking eyes.
A targeted regenerative treatment designed specifically for the delicate skin around the eyes.
Polynucleotides help improve hydration, elasticity and skin texture, reducing the appearance of fine lines, crepey skin and certain types of dark circles.
Unlike tear trough filler, which adds volume, polynucleotides focus on improving the quality of the skin itself, making them an option for those seeking subtle, natural-looking under-eye rejuvenation.
£249 per treatment
Course of 3 – £675
Polynucleotides – Full-Face Skin Regeneration
Healthier, smoother, more resilient skin.
Our full-face polynucleotide treatment focuses on improving overall skin quality through regenerative skin support.
Designed for those experiencing fine lines, dullness, dehydration, reduced elasticity or uneven texture, this treatment helps support collagen production, skin hydration and natural repair processes.
It may also be beneficial as part of a wider treatment programme for redness-prone or stressed skin.
Rather than altering facial volume or structure, the focus is on restoring the skin’s natural vitality, resilience and radiance.
£299 per treatment
Course of 3 – £780
we use carefully selected, professional-grade polynucleotide formulations from Plinest, Plenhyage and Rejuran.
FAQs
Are polynucleotides the same as dermal fillers?
No. Dermal fillers are primarily used to restore volume and enhance facial contours, whereas polynucleotides focus on improving skin quality, hydration, elasticity and regenerative processes.
They are designed for skin rejuvenation rather than facial volumisation.
Are polynucleotides suitable for everyone?
Suitability depends on medical history, skin condition, the specific formulation and any relevant allergies or contraindications. A consultation is required before treatment.
How many treatments will I need?
A course of three treatments is commonly recommended, usually spaced approximately 2–4 weeks apart.
The number and frequency of treatments will depend on the product selected, treatment area and individual skin concerns.
Is there downtime?
Mild redness and small bumps at the injection sites may occur, but these typically subside within a few days. Most clients return to normal activities shortly after treatment, bruising can occur at injection site which can occasionally last longer.
When will I see results?
Many clients notice a subtle glow and improved hydration after the first treatment, with continued improvements in skin texture, tone, and firmness developing over time as the skin regenerates.
Can polynucleotides help dark circles?
Polynucleotides may improve the appearance of certain types of dark circles, particularly where thin, crepey or dehydrated skin contributes to a tired-looking under-eye area.
However, dark circles can also be caused by pigmentation, vascular visibility or structural hollowing, which may require alternative treatments.
Can polynucleotides help with facial redness?
Polynucleotides have potential anti-inflammatory and regenerative properties that may support skin resilience and improve the appearance of some redness-prone skin.
However, they are not a direct treatment for visible thread veins or established vascular lesions. Laser treatments may be more appropriate for these concerns.
How long do results last?
Results vary depending on age, skin condition, lifestyle and the treatment protocol. Maintenance treatments may be recommended every 6–12 months.
What is the difference between polynucleotides and Profhilo & skin boosters
Both treatments focus on skin quality, but they work differently.
Profhilo and skin boosters are a hyaluronic acid-based injectable designed primarily to improve skin hydration and support tissue remodelling.
Polynucleotides are DNA-derived molecules used to support skin repair and regenerative processes, with a focus on improving texture, elasticity and overall skin quality.
The most suitable treatment depends on your skin concerns and goals.